Tri-Heart Plus (Rx)

Get a prescription in 10 minutes
Tri-Heart Plus (Rx)

Why our vets recommend it

Tri-Heart Plus makes it easy and more affordable to protect dogs from heartworm disease, roundworms, and hookworms.

 
 
 
 

Medication information

What is Tri-Heart Plus?

Tri-Heart® Plus is a chewable, monthly prescription medication that protects dogs from the threat of potentially deadly heartworm disease, plus controls roundworms and hookworms. It kills the heatwrom larvae before they reach your dog’s heart. 

 

These beef-flavored chews taste great so they can be given like a treat.

What does Tri-Heart Plus treat?

Tri-Heart Plus prevents heartworm disease. It also treats and controls roundworms and hookworms.

How is Tri-Heart Plus given?

Give Tri-Heart Plus to your pet orally once a month according to the instructions from your veterinarian. Most dogs like the taste, so these beef-flavored chewable tablets can be given like a treat.

Who is Tri-Heart Plus for?

Dogs and puppies 6 weeks of age and older

What are the active ingredients of Tri-Heart Plus?

The active ingredients of Tri-Heart Plus are ivermectin and pyrantel.

What are the possible side effects of Tri-Heart Plus?

The most common side effects of Tri-Heart Plus are depression, lethargy, vomiting, reduced appetite, dilated pupils, loss of coordination, staggering, convulsions, and excessive drooling.

How to get prescriptions from our online vets

1

Pick a plan and become a member

2

Schedule a video call with a licensed vet

3

Order the prescriptions the vet recommends

4

Get unlimited care & follow-ups

Learn more

Safety Information

Do not give to dogs who already have a heartworm infection.1

Warnings 

Do not double up on dosage. If a dose is missed, continue as usual.1

Human Warnings

Keep out of reach of children.1


References

  1. Merck Animal Health. Tri-Heart® Plus Chewable Tablets (ivermectin/pyrantel). Compendium of Veterinary Products, updated 17 May 2024, https://merckusa.cvpservice.com/product/basic/view/1047238. Accessed 6 June 2025.