Trazodone (Rx)

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Trazodone (Rx)

Why our vets recommend it

Trazodone can be a great tool to calm pets in anticipation of stressful situations such as fireworks and vet visits.

 
 
 
 

Medication information

What is trazodone?

Trazodone is an oral tablet that increases the natural serotonin levels in the brain, helping pets stay calmer and reducing anxiety. This fast-acting medication can take effect in as little as 2 hours and stays effective for a relatively short time. This makes it an ideal medication for treating acute anxiety caused by stressful situations (such as going to the vet or flying) as well as noises (such as fireworks or thunder), phobias, and other problems that need temporary relief.

What does trazodone treat?

Common symptoms that trazodone treats include:

  • Whining or barking
  • Pacing
  • Yawning
  • Destructive behavior
  • Panting
  • Hiding
  • Trying to escape

Conditions that trazodone treats include:

  • Anxiety
  • Phobias
  • Behavioral disorders

How is trazodone given?

Give orally to pets with or without food following the dosage instructions from your veterinarian.

Who is trazodone for?

Cats and dogs

What is the active ingredient in trazodone?

Trazodone hydrochloride

What are the possible side effects of trazodone?

The most common adverse effect of trazodone in pets is sedation, though that’s also a desired effect. Gastrointestinal issues can also occur such as vomiting, diarrhea, and loss of appetite. It has also been shown to occasionally cause disinhibition which can lead to increased aggression. If your pet experiences any adverse effects, please discontinue the medication and contact us.

Be sure to tell your vet about any medications, vitamins, or supplements that your pet is taking.

Safety Information

.Side effects may include increased appetite, sedation, nausea, and diarrhea. Giving dose with food may help with nausea. Your vet may recommend beginning at a partial dosage to minimize likelihood of side effects. Talk to your vet about other medications your dog is taking and whether there may be interactions. If you miss a dose, do not double the next dose. Give as normal. 1

Warnings 

  • Serotonin syndrome is a rare but serious side effect. Symptoms may include elevated heart rate, shivering, dilated pupils, difficulty breathing, and high blood pressure. Risk is increased when paired with other serotonin-enhancing drugs or MAO inhibitors. If this occurs, contact your vet immediately. 1
  • Do not use in dogs with heart, liver, or kidney failure. 1

References

  1. Brooks, Wendy. "Trazodone HCL ." Veterinary Partner, veterinarypartner.vin.com/default.aspx?pid=19239&id=7756524. 

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