Trifexis for Dogs (Rx)

  • Prescription
  • Dogs
  • Flea & Tick
  • Heartworm
Trifexis for Dogs (Rx)
Trifexis® Chewable Tablets are beef-flavored chewable tablets administered once a month to protect your dog from heartworm disease, kills fleas and prevents flea infestations, and treats and controls adult hookworms, roundworm and whipworm infections.
Total Price

$135.98

($135.98 / unit)

Price Match Guarantee
Free Shipping
Get vet care and prescriptions, quickly and affordably from home
See how it works

Medication information

What is Trifexis?

Trifexis® is a beef-flavored chewable tablet for dogs that kills fleas and prevents flea infestations, prevents heartworm disease, and treats and controls adult hookworm, roundworm, and whipworm infections. This is a 6-month supply.

What does Trifexis treat?

Trifexis is a monthly medication that:

  • Kills fleas and prevents flea infestations 
  • Prevents heartworm disease
  • Treats and controls adult hookworm, roundworm, and whipworm infections

How is Trifexis given?

Give Trifexis once a month with food for maximum effectiveness. This chewable, beef-flavored tablet that can be given as a treat. 

Who is Trifexis for?

Dogs and puppies 8 weeks and older, weighing 5 lbs or more

What are the active ingredients of Trifexis?

The active ingredients in Trifexis are Spinosad and milbemycin oxime. 

What are the possible side effects of Trifexis?

When used as prescribed, side effects while using Trifexis are rare. The most common side effects include vomiting, fatigue (lethargy), itchy skin, lack of appetite, diarrhea, trembling/shaking, lack of coordination, drooling, reddening of the skin, and seizures.

How Dutch works

  • 1

    Pick a membership plan

    Choose an annual or monthly plan — starting from just $11/month.

  • 2

    Video chat with a vet today

    Pick a time and get care from a licensed vet from home.

  • 3

    Get prescriptions shipped free

    Your vet will customize a treatment plan to help your pet and we’ll ship it to you.

  • 4

    Get unlimited care & follow-ups

    Ask follow-up questions and get care for other health issues quickly online.

Annual members save $650 a year vs. other vets

  • Time to
    see a vet

  • Vet visit fee

  • Unlimited care
    for up to 5 pets

  • 24/7 video calls
    & messaging

  • Medication savings

  • Total annual savings

  • Less than 24 hours

  • FREE

  • Yes

  • Yes

  • 25% OFF

  • Save $650

other vets

  • 2 weeks

  • $100

  • No

  • No

  • No

  • $0