Revolution Plus is a topical combination anti-parasiticide approved for use in cats and kittens of 8 weeks of age and older. This is a monthly topical medication used for the prevention of heartworm, treatment and prevention of flea infestation, and the treatment and prevention of tick infestation, ear mites, roundworms and intestinal hookworms. It is applied using the applicator tube down the back along the skin once monthly. Adverse reactions are very uncommon however lethargy, hair loss at the application site, and decreased appetite have been reported. If any unwanted side effects or changes in behavior or health are detected, this medication should be discontinued and our veterinarians should be notified.