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If your dog suffers from seizures or anxiety, your vet may prescribe gabapentin. Gabapentin is a prescription medication that treats pain, seizures, and anxiety in pets. Because it has different uses, it's crucial to understand gabapentin for dogs' dosage by weight to ensure you're giving them the proper amount based on their current needs.

So what is the gabapentin for dogs dosage by weight? It depends on what your vet is using it to treat and your dog's weight and overall health. Keep reading to learn more about how vets determine the correct gabapentin dosage for your dog.

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What is gabapentin for dogs?

Gabapentin is an anticonvulsant commonly prescribed to treat seizures, pain, and anxiety in dogs. This medication works by modifying the neurotransmitter activity in the brain and is used as an extra-label prescription for pets.

Gabapentin is given by mouth, but the set schedule for your dog will depend on the condition your vet is trying to treat. Ultimately, the gabapentin for dogs dosage by weight will depend on several other factors. For example, the gabapentin for dogs dosage by weight for anxiety may be different from the dosage for treating seizures.

Gabapentin uses for dogs

Gabapentin has a wide range of uses, including treating nerve pain, seizures, and anxiety.

Pain Management

This medication is often used in conjunction with other pain medications like non-steroidal anti-inflammatory drugs (NSAIDs) to reduce pain associated with neuropathy by blocking calcium channels in the central nervous system to prevent particular neurons from being stimulated by pain. Additionally, gabapentin may be effective at reducing chronic joint pain from arthritis and other diseases. However, more research is needed to determine its efficacy in treating pain in dogs.

Seizure prevention

Gabapentin was originally developed to treat seizures, which is why it's classified as an anticonvulsant. While we don't yet know how exactly gabapentin works to control seizures, it's been proven effective at reducing their length and severity.

Anxiety management

Another common use for gabapentin in dogs is for anxiety management. Combined with other anxiety medications, it may drastically reduce symptoms associated with anxiety in dogs. Unfortunately, there's limited research on the efficacy of gabapentin for dogs for anxiety. However, a recent study on the effects of a single oral dose of gabapentin to treat storm phobias in dogs demonstrated a significant reduction of the fear response in dogs given doses of gabapentin ranging from 25 or 30 mg/kg.

List of potential drug interactions with gabapentin

Side effects of gabapentin for dogs

While gabapentin is tolerated well by most dogs, no medication is perfect. However, the side effects associated with gabapentin are generally mild since vets usually prescribe low trial doses to determine the medication's effectiveness and safety. The most common side effects of gabapentin for dogs are tiredness (sedation) and loss of coordination. Other side effects include:

Gabapentin drug Interactions

Gabapentin is commonly prescribed alongside other medications. For example, your dog might take fluoxetine daily and gabapentin before stressful events like going to the vet. However, it may interact with some drugs, so it's crucial to let your vet know if your dog is taking any medication, vitamins, or supplements. Potential drug interactions include:

  • Antacids
  • Hydrocodone
  • Morphine

Can you use gabapentin and trazodone together for dogs?

Yes, gabapentin and trazodone can be used together for dogs, but it's important to consult your vet. These medications can work well together to address anxiety and pain when a vet prescribes the right dosage and combination for your dog's specific needs. Always follow professional guidance to ensure your pet's safety.

Can dogs have CBD and gabapentin together?

CBD and gabapentin can sometimes be used together to manage pain and anxiety in dogs. You should discuss this combination with your vet to avoid any adverse effects or interactions. Your vet will guide you on the appropriate dosages and monitor your dog's response to ensure optimal care.

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Recommended gabapentin dosage for dogs by weight

Gabapentin dosage by weight is the most common way vets determine how much of this medication to administer to your dog. It comes in a variety of doses — 100 mg, 300 mg, 400 mg, and 800 mg — but your dog's particular prescription will depend on the condition being treated. Your vet will consider a range of factors like:

  • Condition-specific dosing: Your dog’s exact gabapentin prescription depends on the condition being treated.
  • Seizure starting dose: For seizures, the typical starting dose is 10 mg/kg twice daily.
  • Seizure dose range: Some dogs may need higher seizure doses of 30–60 mg/kg twice daily.
  • General guidelines: A common general dose is 5 mg/kg every 12 hours.

Every dog and condition is different. For example, the dosage for anxiety may be much higher or lower than the recommended gabapentin dosage by weight for pain. For this reason, vets typically prescribe a low starter dose and ask that pet parents monitor their pets for signs of adverse reactions and report back with changes in their pet's behavior or perceived pain levels.

Since gabapentin dosage for dogs by weight varies greatly depending on the condition, it's crucial to follow your vet's instructions to obtain the desired result. Some dogs may require much higher doses than others.

It's also important to note that gabapentin can take up to two hours for improvement in clinical signs. However, it can take a few weeks to achieve the desired result when given as an anti-seizure medication. Therefore, if your vet prescribed gabapentin to treat your dog's storm phobia, you should administer it at least two hours before the storm hits. As a short-acting medication, it should stop working within 24 hours.

Gabapentin comes in 100 mg, 300 mg, 400 mg, and 800 mg doses

Gabapentin Dosage for Chronic Pain in Dogs

Initial dose: 5–15 mg/kg (2.3–6.8 mg/lb) every 12 hours
Titration (if needed): Increase gradually up to 40 mg/kg (18.1 mg/lb) every 8–12 hours

Dog Weight

Initial Low Dose

Initial High Dose

Titrated Max Dose*

5 lb

12 mg

34 mg

91 mg

10 lb

23 mg

68 mg

181 mg

20 lb

45 mg

136 mg

362 mg

30 lb

68 mg

204 mg

543 mg

40 lb

91 mg

273 mg

724 mg

50 lb

114 mg

341 mg

905 mg

60 lb

136 mg

409 mg

1,086 mg

70 lb

159 mg

477 mg

1,267 mg

80 lb

182 mg

545 mg

1,448 mg

90 lb

205 mg

614 mg

1,629 mg

100 lb

227 mg

682 mg

1,810 mg

*Max dose shown represents the upper end of titration, given every 8–12 hours, only if clinically necessary.

Gabapentin Dosage to Reduce Anxiety in Dogs (Short-Term Use)

Timing: 1–2 hours before the anticipated anxiety-triggering event
Dose: 30–60 mg/kg (13.6–27.3 mg/lb)

Dog Weight

Low Anxiety Dose

High Anxiety Dose

5 lb

68 mg

136 mg

10 lb

136 mg

273 mg

20 lb

273 mg

545 mg

30 lb

409 mg

818 mg

40 lb

545 mg

1,091 mg

50 lb

682 mg

1,364 mg

60 lb

818 mg

1,636 mg

70 lb

955 mg

1,909 mg

80 lb

1,091 mg

2,182 mg

90 lb

1,227 mg

2,455 mg

100 lb

1,364 mg

2,727 mg

Gabapentin typically takes two hours or less to take effect

What happens if you miss a dose of gabapentin?

If you miss a dose of gabapentin, you should wait and give them the next scheduled dose.6 Doubling your dog's dosages could increase their risk of an overdose.

Gabapentin safety

When giving gabapentin to your dog, safety is key. Overdosing can happen if your dog takes too much, and some liquid forms might contain xylitol, which is toxic to dogs. An overdose can lead to dangerous drops in blood sugar and liver damage.

If you suspect an overdose, contact your vet or head to the nearest emergency clinic immediately. You can also reach out to the Pet Poison Helpline at 855-764-7661 for guidance.

To prevent overdoses, your vet will typically start your dog on a low dose to see if it's effective for the condition being treated. They can then adjust the dosage as needed.

Consider using a pill organizer to avoid accidental double dosing. Store medication securely, with a child-proof lid, and out of your dog's reach.

Always consult your vet before giving gabapentin. Even if you have some at home for another pet or human, only give your dog medication prescribed specifically for them. Dosages differ by species and weight, and an old prescription might not be safe for your dog, especially if they have liver or kidney issues.

If your dog takes gabapentin daily, don't stop it suddenly, as this can increase the risk of seizures. Instead, follow your vet’s advice and wean your dog off the medication gradually over a few weeks.

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Gabapentin precautions and warnings

Keeping your dog safe is the top priority. Make sure you follow the vet's instructions closely and watch for any side effects. Store all medications securely, and never share prescriptions between pets or with people. If your dog has other health conditions, like liver or kidney issues, check with your vet to see if gabapentin is suitable.

Alternatives to gabapentin for dogs

When gabapentin isn't the right fit for your pup, there are other options to consider. Non-steroidal anti-inflammatory drugs (NSAIDs) can effectively manage pain by reducing inflammation and providing relief.

For anxiety, behavioral therapies or medications like trazodone might offer calming effects. It's crucial to chat with your vet, as they can help find the best approach tailored to your dog's needs.

In the case of seizures, options like phenobarbital or potassium bromide may be prescribed. Every dog is unique, so always consult with your veterinarian to find the safest and most effective alternative for your pet.

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Get gabapentin online with Dutch

Gabapentin is a versatile medication with a wide range of clinical uses in dogs, from managing chronic pain and seizures to supporting certain anxiety-related conditions. While more research is still needed to fully understand its effectiveness for anxiety, gabapentin has been well studied and is commonly prescribed for pain control and seizure management. In many cases, veterinarians may recommend gabapentin as a trial medication for your dog, adjusting the dose as needed for safety and effectiveness.

If gabapentin is part of your dog’s treatment plan, a Dutch membership can make the process simple and stress-free. With Dutch, you can consult with licensed veterinarians online, get expert guidance on medications and dosing, and have prescriptions like gabapentin delivered directly to your door. This at-home approach helps ensure your dog gets timely care and ongoing support without the hassle of frequent in-clinic visits.

Get gabapentin online today with a Dutch membership.

Gabapentin for Dogs FAQs

How long does it take for gabapentin to work in dogs?

Gabapentin typically starts working in two hours or less. However, if your dog is taking gabapentin daily to treat seizures, pain, or anxiety, it may take a few weeks for you to notice any significant improvements. 

Gabapentin is considered a fast-acting medication, so if you're using it for situational anxiety, you can give it to your dog two hours before a triggering event. For example, if your dog is afraid of the vet, you can give them gabapentin beforehand to help them stay calm.

What does gabapentin do to dogs?

Gabapentin helps manage seizures, pain, and anxiety in dogs by changing how neurotransmitters work in the brain. It’s known for being an effective anticonvulsant and pain reliever, making life a bit more comfortable for your furry friend.

Does gabapentin make dogs sleepy?

One of the side effects of gabapentin is sedation, which is why it makes such a good anxiety medication for dogs. However, the level of sleepiness varies from dog to dog. Some dogs may not feel tired on gabapentin, while others may nap more frequently until the medication wears off.

That said, gabapentin shouldn't overly sedate your dog. Your vet will give your pet a low starting dose, and you should report back with any side effects, including sedation, to help your vet determine whether they should increase or decrease the dose. In some instances, your vet may suggest increasing the dosage on an as-needed basis.

For example, if your dog takes 50 mg of gabapentin every 12 hours to manage their daily anxiety, your vet might recommend they take an additional amount of the medication for triggering events. In this case, they might suggest giving your dog an extra 25 mg of gabapentin two hours before stressful events like vet visits, thunderstorms, or fireworks.

If gabapentin overly sedates your dog, your vet will likely decrease the dose and have you report back to see if there are any improvements in your dog's condition and their overall sleepiness.

Can gabapentin cause drooling in dogs?

Yes, gabapentin can cause drooling in dogs, although it's not very common. If you notice your dog drooling more than usual, it’s wise to check in with your vet for advice.

Is gabapentin a strong painkiller for dogs?

Gabapentin is an analgesic that's well-tolerated by most healthy dogs and can help relieve pain associated with neuropathy and arthritis. It's typically used with other pain medications for dogs, such as NSAIDs or opioids, to further reduce inflammation and pain associated with a wide range of conditions.

Is tramadol or gabapentin better for dogs in pain?

It depends on your dog's needs. Tramadol is often chosen for acute pain, while gabapentin shines when tackling nerve pain. Your vet is the best person to determine which is suitable for your dog.

Learn more about gabapentin and get a prescription online today.


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References

  1. "Gabapentin: Uses, Side Effects, and Safety." Medical News Today, MediLexicon International, https://www.medicalnewstoday.com/articles/323681.

  2. Harari, Joseph. "Pain Management in Small Animals with Lameness - Musculoskeletal System." Merck Veterinary Manual, 22 Mar. 2023, https://www.merckvetmanual.com/musculoskeletal-system/lameness-in-small-animals/pain-management-in-small-animals-with-lameness?query=gabapentin.

  3. "U.S. Service Animals - Gabapentin for Dogs: How It Helps Dogs with Seizures." U.S. Service Animals Blog, 6 Jan. 2023, https://usserviceanimals.org/blog/gabapentin-for-dogs/.

  4. Erickson, Amelia, et al. "A Review of Pre-Appointment Medications to Reduce Fear and Anxiety in Dogs and Cats at Veterinary Visits." The Canadian Veterinary Journal = La Revue Veterinaire Canadienne, U.S. National Library of Medicine, Sept. 2021, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360309/.

  5. Bleuer-Elsner, Stephane, et al. "Effects of a Single Oral Dose of Gabapentin on Storm Phobia in Dogs: A Double-Blind, Placebo-Controlled Crossover Trial." The Veterinary Record, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/33993491/.

  6. “Gabapentin .” MSPCA, Plumb's Veterinary Medication Guides, https://www.mspca.org/wp-content/uploads/2017/04/Plumbs-Gabapentin.pdf.

  7. “Table: Antiepileptic Drugs.” Merck Veterinary Manual, https://www.merckvetmanual.com/multimedia/table/antiepileptic-drugs.

  8. "Is Gabapentin Safe for Dogs?" Drugs.com, https://www.drugs.com/medical-answers/gabapentin-safe-dogs-3570904/.

Frequently asked questions

With Dutch, you’re never alone when it comes to your pet’s health. Whether your pet needs care or you just have a question, our compassionate and knowledgeable vets are always happy to help.

Here are some ways you can use Dutch:

  • Care & prescriptions for over 150 issues
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  • Second opinions & follow-up care after in-person visits
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  • Vet care when you’re traveling
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  • Answers to non-urgent questions

When booking a video call with a vet, you'll be asked a few questions about your pet’s health issue. Depending on the issue, you may also be asked to fill out a longer questionnaire about their symptoms and share photographs of them so our veterinarians can better understand what’s going on. You’ll then pick an appointment time that works best for you.

During your video call, one of our licensed veterinarians will talk to you about the symptoms your pet is experiencing, ask you questions, review your pet’s medical history if you’ve provided it, and answer any questions you have. The vet will ask to see your pet and their environment. And they may ask you to perform some simple checks on them if needed.

After your video call, the vet will send you a message with a custom treatment plan to help your pet feel better, including a link to buy any recommended prescription or over-the-counter medications. Place your order and we’ll ship it free.

Our vets can provide care and prescriptions for more than 150 issues — and over 90% of cases can be treated virtually. 

The vet can diagnose your pet based on your description of their symptoms, their medical history, seeing them during your video call, and, if needed, through uploaded photos and videos. They may ask you to do a few simple checks during the call. We also offer a number of at-home lab test kits for dogs and cats.

The health and safety of pets is our top priority. In the rare case that a vet determines a pet needs to go to a local clinic, they’ll provide a referral and offer advice on how to care for them until they can be seen. 

Some things that require in-person care include emergencies, wounds that need stitches, and issues that require blood work, imaging (X-rays or ultrasounds), or surgery.

Our vets are always available for second opinions and follow-up care after in-person vet visits — so you don’t have to navigate health issues alone.

We offer several membership plans to fit your needs and budget. All of our annual plans include fast, unlimited access to vets via video chat and messaging for up to 5 pets — for one low price.

Prescriptions and any other treatments the vet recommends aren’t included in your membership. The cost of these varies based on what your pet needs. You can browse our pharmacy to get an idea of medication costs. To make your pet’s care as affordable as possible, we offer a price-match guarantee and free standard shipping.

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