Gabapentin vs. tramadol for dogs: Uses, side effects, and dosage

Gabapentin and tramadol are two prevalent pain medications often prescribed for dogs experiencing temporary or chronic pain. Gabapentin specifically targets nerve-induced pain, whereas tramadol, an opiate, offers broad-spectrum pain relief. Both medications are recognized for their effectiveness and are deemed safe for dogs. 

When comparing gabapentin vs. tramadol for canine pain relief, it's clear that each drug operates differently. Depending on the nature and source of the pain, a vet might prescribe either one of these medications or even both in some cases. The primary objective of using these drugs is to manage pain, ensuring comfort for dogs whether they're facing a brief bout of pain or an enduring pain source.

Read on to learn more about tramadol vs. gabapentin for dogs, and why your vet might choose them for your dog.

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• What Is Gabapentin?
• What Is Tramadol?
• Comparing Gabapentin And Tramadol For Dogs
• Which Medication Is Right For Your Dog?
• FAQs
• Final Notes

What is gabapentin for dogs?

Gabapentin is an anticonvulsant used to treat a number of neurological disorders. Often sold under the brand names Neurontin, FusePaq, Fanatrex, Gabarone, Horizant, and Gralise, it’s primarily used to treat epilepsy in humans, but can also be used for nerve pain caused by shingles, diabetes, and injury.

Gabapentin is often prescribed for dogs off-label, which means it hasn't received FDA approval specifically for canine use. However, off-label prescriptions are a widespread and generally safe practice in veterinary care, tailored to a pet’s specific needs under a vet's guidance. Consult your vet if you have any questions or concerns.

In veterinary medicine, gabapentin is available in the following form:

• Capsules
• Tablets
• Oral solution
• Compounded version for dogs that need a customized formula or flavor

Gabapentin uses

Gabapentin can be used for a variety of conditions and situations, including:

• Pain: Gabapentin is often prescribed to alleviate chronic pain, especially nerve-related pain.
• Seizures: It can be used as an adjunctive therapy for controlling seizures in dogs.
• Anxiety: Some vets prescribe gabapentin to reduce anxiety, especially during events like thunderstorms or fireworks.
• Post-operative care: It can be given to dogs after surgeries to manage pain and provide comfort.

Gabapetin side effects

The common side effects of gabapentin in dogs include:

• Excitability
• Depression
• Oversleeping
• Diarrhea
• Nausea
• Vomiting
• Lightheadedness
• Shakiness
• Increase in appetite
• Lack of coordination

Gabapentin dosage

In terms of how much your dog should take and how often, it is crucial to consult your vet. While the Merck Veterinary Manual suggests 10 mg/kg and up to 30–60 mg/kg three times a day by mouth, every dog is different.

Learn more about gabapentin for dogs and get a prescription online today.

What is tramadol for dogs?

Available under the brand names ConZip, Durela, Ultram, Tridural, Qdolo, Ralivia, and Rybix, tramadol is a synthetic opioid used to provide relief from moderate to moderately severe pain in humans. It acts by limiting the brain's reuptake of serotonin and norepinephrine, which in turn reduces the spinal cord's capacity to transmit pain signals to the brain.

Tramadol uses

Tramadol is used to treat many different types of pain in dogs, including:

• Acute pain: Tramadol can address sudden and severe pain resulting from injuries or trauma. 
• Chronic pain: Dogs with long-standing issues can benefit from tramadol's pain-relieving properties.
• Post-operative pain: Following surgical procedures, tramadol provides relief during recovery.

• Cancer-related pain: For dogs diagnosed with cancer, tramadol offers relief from pain caused by the disease or its treatment.

Tramadol side effects

Most dogs tend to tolerate tramadol well, but like with any medication, they can still experience certain side effects, including:

• Constipation
• Diarrhea
• Anxiety
• Drowsiness
• Dizziness
• Tremors
• Nausea
• Loss of appetite

Tramadol dosage

The dosage prescribed for your dog depends on their weight. Typically, a dose of 4–10 mg/kg is administered orally every 6 to 12 hours. However, based on the nature of the pain and your dog's specific needs, your vet might adjust this dosage. Always follow your veterinarian's recommendations.

Comparing gabapentin and tramadol for dogs

Gabapentin and tramadol, while both utilized for pain relief in dogs, function distinctively in addressing pain origins. Gabapentin, primarily used for neuropathic and chronic pain, targets discomfort arising from the nervous system. Its unique mechanism makes it particularly effective for conditions where nerve damage or dysfunction is evident. 

On the other hand, tramadol is an opioid-based analgesic, more broad-spectrum in its approach. It's commonly prescribed for acute pain scenarios, such as intense discomfort or post-op recovery. While gabapentin is typically well-tolerated and can be used alongside other pain medications, tramadol, being an opioid, has potential for more significant side effects and may cause dependency if used long-term. 

Despite their differences, both medications should always be administered under strict veterinary guidance to ensure the safety and well-being of your pet.

The benefits of using gabapentin and tramadol together for pain management

Gabapentin and tramadol can be used together in dogs under the supervision of a vet. When combined, they can offer synergistic effects for pain management, particularly for dogs with chronic or severe pain conditions. Combining these medications can allow for lower doses of each drug, potentially minimizing side effects. Your vet may also prescribe a dog-safe non-steroidal anti-inflammatory drug (NSAID) in conjunction with tramadol and gabapentin for dogs who are in acute pain and need maximum pain relief. 

Gabapentin and tramadol drug interactions

Gabapentin and tramadol are sometimes prescribed together for dogs because they manage pain through different mechanisms. When used concurrently, their sedative effects may increase, leading to drowsiness, lethargy, or coordination issues, especially when starting treatment or adjusting doses.

Both medications can also interact with other drugs, particularly those affecting the central nervous system. Tramadol may interact with medications that influence serotonin levels, while gabapentin can enhance the effects of sedatives, making your dog sleepier or more lethargic. A veterinarian should always review your dog’s full medication list to ensure safe use.

Gabapentin vs. tramadol: How to choose the best medication for your dog?

Before choosing tramadol or gabapentin for your dog's pain, always consult your vet. Both meds require a prescription and the prescribed dosage may vary based on your dog's specific pain issue. The first step is a vet check-up to identify the cause of the pain. After evaluating your dog, the vet will recommend either tramadol, gabapentin, or possibly a combination, considering the nature of the pain and any other health factors. They may also prescribe a different medicine, such as a NSAID.

Here are some of the factors your vet will consider before prescribing your dog gabapentin:

• Diagnosis: Your vet conducts various tests and imaging to pinpoint the cause of your dog's pain and solidify their preliminary diagnosis. 
• Medical history: Reviewing your dog's past health issues and previously prescribed medications provides context.
• Known allergies and sensitivities: Some dogs might be allergic or sensitive to ingredients in medications. The vet checks for any signs your dog might not tolerate certain drugs.
• Drug interactions: If your dog is already on medication, your vet checks for any possible adverse reactions with gabapentin and tramadol. If there's a known negative interaction, alternative pain relievers may be considered.
• Type and severity of pain: The vet examines the type and intensity of your dog’s pain. Their prescription will align with these findings.
• Age and weight: Your dog's age can influence medication decisions. As dogs age, their response to medication can change. Meanwhile, weight is crucial for determining the correct dosage to ensure effective pain relief.
• Side effects: Both gabapentin and tramadol have potential side effects. By examining your dog's history and any past drug intolerances, the vet can make an informed choice.
• Cost: If two medications are equally effective but one is cheaper, the vet will discuss the pros and cons with you.

Considering all these factors, your vet will make the best medication choice for your dog. Always feel free to discuss any concerns or questions with your vet, ensuring you're well-informed and confident in the care your dog receives.

Keep your dog pain-free with gabapentin from Dutch 

Choosing gabapentin vs. tramadol for your dog ultimately depends on the type, severity, and cause of their pain. It's helpful to know about these pain relief options for your dog, but it's crucial to engage in a conversation with your vet before deciding on any medication. 

At Dutch, we provide accessible online vet care, offering customized treatments for your pet. From arthritis to UTIs, our team can address a variety of conditions. With Dutch, there's no need to disrupt your pet's comfort by making them travel, especially when they're in pain. Experience the convenience of Dutch and get your pet’s prescriptions delivered free straight to your door from our online pharmacy.

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Gabapentin vs. tramadol FAQs

Why do vets prescribe tramadol for dogs?

Vets prescribe tramadol to manage moderate to severe pain in dogs, including post-surgical pain, injuries, arthritis, and chronic conditions. It works by changing how the brain processes pain rather than reducing inflammation.

Tramadol is often chosen because it can be safely combined with other pain medications, such as gabapentin or NSAIDs, allowing vets to customize pain relief based on a dog’s needs.

Can I give my dog gabapentin and tramadol at the same time?

While it's possible to give your dog both medications concurrently, it's crucial to do so only under your veterinarian's guidance.

Are there OTC pain meds for dogs?

Over-the-counter pain medications for dogs are not recommended without veterinary guidance. It's crucial to consult a veterinarian for any concerns about your dog’s pain management. Using human medications can be harmful and ineffective for your furry friend, so it’s crucial to prioritize their well-being with professional advice.

How can I tell if my dog is in pain?

Dogs exhibit pain in varied ways. Some symptoms may develop slowly, while others can be sudden. They might start favoring a limb or become sensitive in a particular area. Common indicators of pain in dogs include:

• Yelping or other vocalizations
• Flattened ears
• Lethargy
• Reduced appetite
• Limping and/or stiffness.
• Unable to keep up during walks
• Reluctance to jump, run, play, or engage in other activities

Can dogs take CBD and gabapentin?

Yes, CBD and gabapentin are sometimes used together in dogs, but only under veterinary guidance. Both can cause sedation, so combining them may increase drowsiness or coordination issues, especially when starting treatment or adjusting doses.

Is tramadol or gabapentin better for dogs in pain?

Neither medication is better in every case — it depends on the type of pain. Tramadol is often used for moderate to severe pain, while gabapentin is typically preferred for nerve-related or chronic pain, and they’re sometimes prescribed together for enhanced relief.

Can gabapentin cause diarrhea?

Yes, diarrhea is a possible side effect of gabapentin in dogs, though it’s less common than drowsiness or lethargy. Gastrointestinal side effects are usually mild, but you should contact your vet if diarrhea persists or worsens.